81377  München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Prof. Haass started to work on Alzheimer's disease (AD) hinein 1990 at a time, when very little was known about the cellular mechanisms involved. Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß. Christian Haass hypothesized against the widely accepted general opinion rein this field that Aß may be produced from its precursor in a physiologically üblich pathway and not necessarily in a pathological process. Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions. This pivotal finding welches a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved in generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production in patients.
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We are using interdisciplinary approaches ranging from biophysics, biochemistry and cellular and molecular biology to hinein vivo models and life imaging.
Together with an interdiziplinary Mannschaft he uncovered the molecular mechanisms of Alzheimer's disease and identified target molecules for therapeutic treatment.
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Welches ich am besten fand artikel die Fahrstunden mit Joachim, wirklich ein toller Fahrlehrer bei dem du wirklich Dasjenige Gefühl bekommst das es ihn spaß macht dir das alles beizubringen. Wurde es nahelegen An diesem ort dein copyright zu machen außerdem wenn es m…
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Gut: Ich habe leider nicht an meine Termin erscheinen zumal nehme ich komplett Verantwortung aber habe ich erwartet Dasjenige nach minderst die Halbe menge oder eine Wertschein erwartet leider habe ich meine Komplet Geld Unrettbar.
Christian Haass, Professor of Metabolic Biochemistry at LMU Munich and spokesperson for the DZNE Munich, is known for his groundbreaking research in Alzheimer's disease. His work focuses on the molecular and cellular mechanisms of this disease rein order to gain fundamental insights into its development.
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